Glatiramer acetate anaphylaxis: detection of antibodies and basophil activation test.
نویسندگان
چکیده
منابع مشابه
Anaphylaxis to Glatiramer Acetate
Glatiramer acetate (Copaxone, Teva Pharma) and interferon beta are the two only disease-modifying therapies for multiple sclerosis. Glatiramer acetate is known for frequently simulating mild, anaphylactoid reactions while true, IgEmediated allergic reactions have been hardly reported so far. Herein, we report two females suffering from multiple sclerosis who experienced rapidly aggravating hype...
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Beef allergies are relatively rare, especially in adults. However, clinical manifestations can vary from urticaria, angioedema, anaphylaxis to gastrointestinal symptoms. Currently available tests, such as skin testing or in vitro determination of beef-specific immunoglobulin E (IgE), do not provide an accurate diagnosis of beef allergy. The recent development of the basophil activation test (BA...
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The diagnosis of insect venom allergy and the indication for specific immunotherapy is based on history, skin tests and demonstration of hymenoptera venom-specific IgE-antibodies. Cellular tests can add useful information but the role of basophil activation tests for the different venoms has to be elucidated further. We evaluated positive reactions in a basophil activation test using CD63 expre...
متن کاملAnaphylaxis by antihistamine containing bovine gelatin: the utility of the basophil activation test in the diagnostic work-up
Address for correspondence: Dr Eleonora Nucera, Allergy Unit, Università Cattolica del Sacro Cuore, Policlinico “A. Gemelli”, Largo F. Vito, 1-00168 Rome, Italy, phone: +39 0630154965, fax: +39 0630156999, e-mail: [email protected] Received: 10.02.2016, accepted: 9.07.2016. Anaphylaxis by antihistamine containing bovine gelatin: the utility of the basophil activation test in the dia...
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عنوان ژورنال:
- Journal of investigational allergology & clinical immunology
دوره 22 1 شماره
صفحات -
تاریخ انتشار 2012